COVID-19 pandemic
2020 pandemic caused by SARS CoV 2 virus. Pandemic had been more of a matter of when rather than whether. Many scientists were anticipating and warning about a pandemic (see Bill Gates‘s TED talk) and there existed estimates of the potential loss from the pandemic (Fan2018pandemic).
One surprise of this pandemic was that many rich, scientifically advanced countries botched the response while many poorer countries have managed it much better. For instance, take a look at this article: What the US can learn from how African countries handled Covid.
It also teaches a lot about Epidemic surveillance testing, a whole plethora of social issues that epidemic spreading can bring about, and the fact that Counting is hard.
Data
Lessons
- People’s behavior has a paramount importance
- Appropriate intervention should look like an over-reaction. That’s why it is really difficult to keep doing it.
- People’s perception gets distorted a lot afterwards.
- Contact tracing matters.
- Vaccine rules, but mutations will follow.
Ruggeri2023synthesis (A synthesis of evidence for policy).
There are also interesting studies about how well scientists/laypeople could predict what would happen: Recchia2021how and Hutcherson2022accuracy.
Mode of spreading and prevention efforts
The transmission through large droplets and the surface has been identified as an important concern at the beginning. Although evidence for airborne, aerosol-based transmission has been mounting, a lot of efforts have been misdirected. Instead of focusing on ventilation, deep cleaning, plexiglass, etc. have been highly active.
Zeynep Tufekci has been talking about this issue. e.g., his thread on a mystery transmission from New Zealand. (Eichler2021transmission)
Social Inequality of pandemic
- Mena2021socioeconomic - Socioeconomic status determines COVID-19 incidence and related mortality in Santiago, Chile
- The Fullest Look Yet at the Racial Inequity of Coronavirus by The New York Times
Measuring outbreaks
It is not trivial to accurately measure the scale of the outbreaks. In the early stage, there was not enough testing capacity and people did not know about the disease. Furthermore, there are a lot of asymptomatic COVID-19 infections. For instance the mass testing in Iceland showed that about half of the carriers shows no symptom. Therefore it is very hard to accurately estimate the number of cases.
Even the number of deaths caused by the outbreak is not trivial to estimate. Again at the beginning, given the absence of tests, someone who died from related symptoms may not be counted. See for instance Coronavirus UK death toll: why what we think we know is wrong on The Guardian.
Using sewage was an alternative population-level measurement method.
See Measurement
Modeling epidemic
- Aleta2020modelling: Modelling the impact of testing, contact tracing, and household quarantine on second waves of COVID-19
- Chang2020mobility: Mobility network models of COVID-19 explain inequities and inform reopening
Economic implications
Healthcare implications
- The impact of missed preventive medical care
- Prescription Fill Patterns for Commonly Used Drugs During the COVID-19 Pandemic in the United States
- Effects of the COVID-19 Pandemic on Outpatient Providers in the US
- Effects of State COVID-19 Closure Policy on NON-COVID-19 Health Care Utilization
Elimination vs. mitigation
Infodemic
A study claimed that the biggest source of misinformation has been president Donald Trump1, who publicly touted many unproven therapies. See Internet Searches for Unproven COVID-19 Therapies in the United States
See also Hydroxychloroquine. The rise and fall of (you know what) walks through the issues with Hydroxychloroquine and Ivermectin.
An important infodemic is about vaccines. COVID 19 vaccine
In Korea, a retired professor 이왕재 produced a lot of misinformation.
Social media
- Chen2022charting studies infodemic across the globe during the pandemic.
Interventions
Perra2021nonpharmaceutical reviews non-pharmaceutical interventions.
This pandemic highlighted the effectiveness of Mask wearing for airborne diseases.