COVID 19 pandemic
How do these vaccines work?
- Vox: Why you can’t compare Covid-19 vaccines
- The potent power of basic research
Ioannou2022effectiveness examines the effectiveness of a third mRNA vaccine dose (booster) against the Omicron variant and showed that the booster was effective, especially against death.
Concerns about blood clotting
- 백신 접종 부작용 혈전증, 이것만 기억하라! | 혈전증 치료 전문가 순환기내과 나상훈 교수: 한국인 관점에서 어떻게 판단해야 하는지 요약
The curious case of AstraZeneca’s Covid-19 vaccine
She points to the story of the first vaccine for Lyme disease, developed by SmithKline Beecham in the late 1990s. The clinical trials for the vaccine showed that arthritis occurred at similar rates in both the vaccine and placebo groups. But media reports and suits by plaintiff’s lawyers led to fears among members of the public. Even after a panel of outside advisers to the FDA voted that the vaccine’s benefits outweighed its risks, sales fell so low that the company withdrew the vaccine from the market.
Around mid-March 2021, Germany stopped the vaccination of AstraZeneca’s vaccine due to the concern about rare sinus venous thrombosis.
- ‘It’s a very special picture.’ Why vaccine safety experts put the brakes on AstraZeneca’s COVID-19 vaccine
- EU agency says AstraZeneca vaccine is ‘safe and effective’
- Norwegian experts say deadly blood clots were caused by the AstraZeneca covid vaccine
- PEI: FAQ – Temporary suspension of COVID-19 vaccine AstraZeneca
It doesn’t seem to be a crazy conspiracy, but potentially due to other reasons (other drugs, multiple hypothesis testing). Also, it seems much more prevalent in Western Europe.
Pfizer and Moderna may have a similar potential side effect (not confirmed): Lee2021thrombocytopenia
There is also a claim of a potential mechanism that links vaccine to the disease although it has not been confirmed yet: AstraZeneca: German team discovers thrombosis trigger
It has been reported that mRNA vaccines may cause mild Myocarditis in the younger, male population.
COVID-19 infection is also known to cause unusual Menstruation I believe.
Abbasi2022widespread discusses the misinformation about infertility.
Barda2022impact reported an increased sperm count. 2021sperm shows a significant increase in sperm count and speculated that it may be due to more abstinence from vaccination. Safrai2022BNT162b2 reported no significant change.
Some argues the sudden cardiac arrest of athelets as evidence of the vaccine’s side effect. However, it is a well-known phenomenon: https://en.wikipedia.org/wiki/Sudden_cardiac_death_of_athletes
In the United States approximately 8 to 10 deaths per year can be attributed to sudden cardiac death in NCAA with overall rate of 1 per 43,000.1
Some people who spread anti-vaccination propaganda
It has been argued that mere 12 people spread the majority of misinformation. (Guardian article and Report)
Vaccine communication strategies
There has been a strong partisan divide regarding vaccination: https://twitter.com/charles_gaba/status/1496199822327562247
Fox News has been spreading a lot of doubts about vaccination although the company imposed a sort-of vaccine pass internally.
Spillover to other vaccines
Trujillo2022covid 19 examines spillover effects to other vaccines.
Because the fatality rate highly depends on the age, the vaccination has been targeted towards older population. Lavine2021vaccinating.
- Epidemiological and evolutionary considerations of SARS-CoV-2 vaccine dosing regimes
Asif, Irfan M.; Harmon, Kimberly G. (2017-02-01). “Incidence and Etiology of Sudden Cardiac Death: New Updates for Athletic Departments”. Sports Health. 9 (3): 268–279. doi:10.1177/1941738117694153. ISSN 1941-7381. PMC 5435153. PMID 28452637; Harmon, Kimberly G.; Asif, Irfan M.; Maleszewski, Joseph J.; Owens, David S.; Prutkin, Jordan M.; Salerno, Jack C.; Zigman, Monica L.; Ellenbogen, Rachel; Rao, Ashwin; Ackerman, Michael J.; Drezner, Jonathan A. (2015-07-07). “Incidence, Etiology, and Comparative Frequency of Sudden Cardiac Death in NCAA Athletes: A Decade in Review”. Circulation. 132 (1): 10–19. doi:10.1161/CIRCULATIONAHA.115.015431. ISSN 0009-7322. PMC 4496313. PMID 25977310. ↩