Deep representation learning of protein-protein interaction networks for enhanced pattern discovery

• https://www.science.org/doi/10.1126/sciadv.adq4324
• RUI YAN, MD TAUHIDUL ISLAM, AND LEI XING

Protein protein interaction network, Graph embedding

discriminative network embedding (DNE) is a Contrastive learning method that uses sampled neighbors as positive sample and degree-based-sampled non-local nodes as negative samples.

The encoder uses Laplacian eigenvectors and optional node features to learn node embeddings.